Stroke patients with cancer had a higher in-hospital post-stroke mortality and more frequent coagulation disorders compared to matched non-cancer stroke patients.
Observational (n=138)
No
Does a concurrent cancer diagnosis alter risk factors, stroke patterns, and in-hospital mortality in patients presenting with stroke?
Stroke patients with comorbid cancer exhibit distinct coagulation profiles and face higher in-hospital mortality, highlighting the need for specialized management.
OBJECTIVE: To investigate risk factors, stroke pattern and outcome in stroke patients with cancer. METHODS: A retrospective review of all stroke patients with cancer (n = 69) admitted to Bankstown-Lidcombe Hospital, Sydney, Australia, between January 1999 and December 2004 was conducted, and comparison made to age- and gender-matched non-cancer stroke patients admitted to the same hospital during the same period. RESULTS: Vascular risk factors did not significantly differ between cancer and non-cancer groups. There was a trend towards greater risk of intracerebral haemorrhage in the cancer group vs the non-cancer group. Previous deep vein thrombosis was more common, and prothrombin time and activated partial thromboplastin time were prolonged in the cancer group vs the non-cancer group. More patients died in hospital in the cancer group vs the non-cancer group. CONCLUSIONS: Coagulation disorders are more likely to be seen in stroke patients with cancer, and patients with cancer have a higher in-hospital post-stroke mortality.
Zhang et al. (Thu,) conducted a observational in Stroke with concurrent cancer (n=138). Cancer (exposure) vs. Age- and gender-matched non-cancer stroke patients was evaluated on Risk factors, stroke pattern, and in-hospital mortality. Stroke patients with cancer had a higher in-hospital post-stroke mortality and more frequent coagulation disorders compared to matched non-cancer stroke patients.