Why the study?
What is the time variation of mitral regurgitant flow during the cardiac cycle in patients with severe heart failure?
Population
8 patients with severe heart failure
Design
Cross-sectional
Authors
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MR occurs mainly during ejection in severe HF; challenges prior angiographic estimates but leaves open therapeutic implications.
What is the time variation of mitral regurgitant flow during the cardiac cycle in patients with severe heart failure?
In patients with severe heart failure, mitral regurgitation occurs predominantly during the aortic ejection period, contrasting with previous angiographic studies.
Keren et al. (1986) studied this question.
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