Key result
First onset atrial fibrillation lasting <48 hours was associated with a higher rate of spontaneous conversion to sinus rhythm compared to AF lasting >48 hours (77% vs 36%; OR 5.9; P<0.001).
Observational (n=438)
Answers are grounded in this paper and cite their sources.
More than half of patients with first-onset atrial fibrillation spontaneously convert to sinus rhythm, with the probability increasing significantly if the AF duration is less than 48 hours.
BACKGROUND/AIM: We studied all patients admitted to hospital with first onset atrial fibrillation (AF) to determine the probability of spontaneous conversion to sinus rhythm and to identify factors predictive of such a conversion. METHODS: We retrospectively reviewed charts of 438 consecutive patients admitted to hospital with first onset AF from 1 January 2006 to 31 December 2009. The patients were divided into two groups, recent onset AF defined as AF < 48 h or longer lasting AF, defined as AF > 48 h. RESULTS: Spontaneous conversion occurred in 54% (n = 203; 95% confidence interval: 49-59%). In the group with first onset AF < 48 h, spontaneous conversion occurred in 77%, compared with 36% in the group with first onset AF > 48 h. Logistic regression analysis identified duration of AF as a highly significant predictor of spontaneous conversion to sinus rhythm (odds ratio 5.9; 95% confidence interval: 4.0-8.6, P < 0.001). CONCLUSIONS: Spontaneous conversion occurred in 54%, increasing to 77% when AF had persisted less than 48 h.
No takes yet. Share an insight, caveat, or question.
Lindberg et al. (2011) conducted an observational in First onset atrial fibrillation (n=438). Atrial fibrillation duration < 48 hours vs. Atrial fibrillation duration > 48 hours was evaluated on Spontaneous conversion to sinus rhythm (OR 5.9, 95% CI 4.0-8.6, p=< 0.001). First onset atrial fibrillation lasting <48 hours was associated with a higher rate of spontaneous conversion to sinus rhythm compared to AF lasting >48 hours (77% vs 36%; OR 5.9; P<0.001).
Synapse has enriched 10 related papers. Consider them for comparative context: