Key result
Antithrombotic therapy utilization in 111 AF patients showed predominant anticoagulant use in valvular AF, while 45.45% of non-valvular AF patients received warfarin and 18.18% received no therapy.
Why the study?
What is the utilization pattern of antiplatelet and anticoagulant medicines among patients suffering from atrial fibrillation?
Observational (n=111)
What is the utilization pattern of antiplatelet and anticoagulant medicines among patients suffering from atrial fibrillation?
Answers are grounded in this paper and cite their sources.
The study highlights the utilization patterns of antithrombotic therapy in Indian AF patients, showing a significant proportion of NVAF patients receiving aspirin or no therapy despite high stroke risk scores.
Background: Antithrombotic therapy is recommended in atrial fibrillation (AF) patients due to high risk of stroke. However, antithrombotic therapy is often underutilized due to adverse effects and limited data available in Indian population. Aims: Primary objective was to study usage pattern of antiplatelet and anticoagulant drugs in AF patients. Secondary objective was to assess the risk of stroke and compare usage pattern of antithrombotic drugs in non-valvular atrial fibrillation (NVAF) patients with application of CHADS2 and CHA2DS2-VASc score. Materials and Methods: A prospective and observational study was conducted in outpatient department for period of one year in patients > 35 years of either gender diagnosed with AF due to any established cause. CHADS2 and CHA2DS2-VASc score were used to assess risk of stroke among NVAF patients. Results: 111 patients diagnosed with AF (mean age 54 years; 54.96% female) were analyzed and out of these, 78 patients were valvular AF patients and 33 were NVAF patients. Anticoagulants were predominantly prescribed in 60 valvular AF patients. Out of 33 NVAF patients, 19 (57.57%) patients had CHADS2 score 1 while as per CHA2DS2-VASc score 28 (84.84%) patients had score 2. Out of 33 NVAF patients, 15 (45.45%) patients were prescribed warfarin, aspirin in 12 (36.36%) patients and no antithrombotic therapy in 6 (18.18%) patients.
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Jadav et al. (2016) conducted an observational in Atrial Fibrillation (n=111). Antithrombotic therapy (antiplatelets and anticoagulants) was evaluated on Usage pattern of antiplatelet and anticoagulant drugs in AF patients. Antithrombotic therapy utilization in 111 AF patients showed predominant anticoagulant use in valvular AF, while 45.45% of non-valvular AF patients received warfarin and 18.18% received no therapy.
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