What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Hypertensive crisis (n=1546). Intervention: Male sex vs. Female sex. Primary outcome: Hypertensive emergencies vs urgencies (OR 1.34, 95% CI 1.06-1.70).

April 2, 2014PLoS ONEOpen Access

Hospital Admissions for Hypertensive Crisis in the Emergency Departments: A Large Multicenter Italian Study

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Key result

Men had a 34% higher likelihood of presenting with hypertensive emergencies rather than urgencies compared to women of similar age (OR 1.34).

Population

1,546 adults aged 18 years and over admitted to 10 Italian Emergency Departments during 2009 for…

Design

Cross-sectional

Authors

GPGiuliano PinnaFondazione FADOI CPClaudio PascalePresidio Ospedaliero PFPaolo FornengoDepartment of Medical Sciences

Discussion

Member takes

Implication

May support sex-stratified risk awareness in ED hypertensive crises; hypothesis-generating and should not yet change practice.

Study Design

Type

Cross-Sectional (n=1,546)

Multicenter

Yes

Structured PICO

Population

1,546 adults aged 18 years and over admitted to 10 Italian Emergency Departments during 2009 for hypertensive crises (systolic blood pressure ≥220 mmHg and/or diastolic blood pressure ≥120 mmHg). Mean age 69.0 years, 48.4% men.

Outcome

Frequency of hypertensive crises among ED admissions, proportion of hypertensive emergencies vs urgencies, and variables independently associated with hypertensive emergencies.

Main Result

Effect estimate: OR 1.34 (95% CI 1.06-1.70)

Absolute Event Rate: 27.8% vs 22.9%

Hypertensive crises account for nearly 5 per 1,000 ED admissions, with men showing lower compliance to treatment and a higher risk of presenting with life-threatening hypertensive emergencies.

Limitations

Data were not population-based, preventing estimation of true hospital admission rates for hypertensive crises.
One recruiting center was excluded due to modified methods of data collection.
Women affected by eclampsia and pre-eclampsia were not included.
Results cannot be extrapolated to populations with a larger proportion of ethnic groups at high risk for hypertensive crises, as 97% of patients were European.
Data were not population-based, preventing estimation of hospital admission rates for hypertensive crises over the study period.
Cross-sectional design does not allow inferences on temporal trends of hypertensive crises.
Study population was predominantly European (97%), limiting extrapolation to other ethnic groups at high risk for hypertensive crises.

Cite This Study

Pinna et al. (2014) conducted a cross-sectional in Hypertensive crisis (n=1,546). Male sex vs. Female sex was evaluated on Hypertensive emergencies vs urgencies (OR 1.34, 95% CI 1.06-1.70). Men had a 34% higher likelihood of presenting with hypertensive emergencies rather than urgencies compared to women of similar age (OR 1.34).

synapsesocial.com/papers/6a1c1fc2ea84844e355f7aa4 https://doi.org/10.1371/journal.pone.0093542

Topics

Hypertension management

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Hospital Admissions for Hypertensive Crisis in the Emergency Departments: A Large Multicenter Italian Study

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Topics

Hospital Admissions for Hypertensive Crisis in the Emergency Departments: A Large Multicenter Italian Study

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Also Consider

Topics

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