Key result
Delayed-enhancement cardiac magnetic resonance imaging detected significantly more left ventricular thrombi (20 cases) than standard transthoracic echocardiography (8 cases) in patients with ischemic DCM.
Why the study?
Left ventricular thrombus is usually underestimated by TTE in patients with DCM, whereas CMRI is promising for detection, but comparative diagnostic ability and predisposing variables required assessment.
Does DE-CMRI improve the detection of left ventricular thrombus compared to TTE and cine-CMRI in patients with ischemic dilated cardiomyopathy?
Observational (n=76)
No
Does DE-CMRI improve the detection of left ventricular thrombus compared to TTE and cine-CMRI in patients with ischemic dilated cardiomyopathy?
Absolute Event Rate: 20% vs 8%
p-value: p=0
DE-CMRI is superior to standard TTE and cine-CMRI for detecting left ventricular thrombus in patients with ischemic dilated cardiomyopathy, and extensive myocardial scarring is an independent marker for thrombus presence.
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May enhance LV thrombus detection in ischemic DCM; hypothesis-generating and requires prospective validation before practice change.
Mehana et al. (2021) conducted an observational in Ischemic dilated cardiomyopathy (n=76). Delayed-enhancement cardiac magnetic resonance imaging (DE-CMRI) vs. Transthoracic echocardiography (TTE) was evaluated on Detection of left ventricular thrombus (p=0). Delayed-enhancement cardiac magnetic resonance imaging detected significantly more left ventricular thrombi (20 cases) than standard transthoracic echocardiography (8 cases) in patients with ischemic DCM.
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