Key result
Left atrial enlargement was present in 57.7% of hypertensive Nigerian subjects and was significantly associated with older age, higher waist circumference, and left ventricular hypertrophy.
Why the study?
Left atrial enlargement predisposes to arrhythmias, atrial thrombogenesis, and cardioembolic stroke, but whether it constitutes a major risk among African hypertensive subjects is not well described.
Cross-Sectional (n=414)
Yes
Left atrial enlargement is highly prevalent (57.7%) among treated hypertensive Nigerians and correlates significantly with age, waist circumference, and left ventricular hypertrophy.
Supports LAE evaluation in African hypertensives; leaves open its independent prognostic value.
Background: Left atrial enlargement (LAE) predispose to arrhythmias, atrial thrombogenesis and cardioembolic stroke. Whether LAE constitute a major risk among African hypertensive subjects is not well described. This study was aimed to describe the epidemiologic pattern of LAE among hypertensive subjects and determine their correlates. Methods: Clinical and demographic details of 414 hypertensive subjects used were taken. Echocardiography was done. LAE was defined as Left atrial dimension (LAD)>3.7 cm. Statistical analysis was done using SPSS 17.0. Result: 414 subjects including 258 (62.3%) males were recruited. The mean age was 56.8±16.8 years. LAE was present in 57.73% of hypertensive subjects. Those with LAE were likely to be older (58.23±14.5 vs. 54.8 ±19.7 years, p<0.05), had a higher waist circumference (88.1 ±26.8 ±75.8 ±28.4 cm, p<0.05), left ventricular mass index (79.2 ± 12.4 vs. 48.7 ±15.5g/m2.7, p<0.05) and a higher frequency of left ventricular hypertrophy (LVH) (65.3% vs. 40.0 %, p<0.05) respectively than those without LAE. LAD was significantly higher among those with LVH than those without LVH (41.4 ±8.4 vs. 35.6 ±5.9 mm respectively, p<0.05). Conclusion: LAE is common among Nigerian hypertensive subjects. Age, waist circumference, left ventricular wall dimension and mass index are the important correlates of LAE in hypertensive Nigerians.
No takes yet. Share an insight, caveat, or question.
Adeseye A. Akintunde (2022) conducted a cross-sectional in Hypertension (n=414). Left atrial enlargement was present in 57.7% of hypertensive Nigerian subjects and was significantly associated with older age, higher waist circumference, and left ventricular hypertrophy.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: