Key result
Model using age, hypertension, and diabetes achieves a 0.7 AUC for identifying CKD.
Why the study?
CKD is associated with disability, low quality of life, and mortality, but most cases are asymptomatic and detected late or incidentally. The study aimed to determine CKD prevalence and develop a predictive nomogram for Vietnamese adults.
Cross-Sectional (n=1,490)
Effect estimate: AUC 0.7 (95% CI 0.65-0.73)
A simple predictive model incorporating age, hypertension, and diabetes can facilitate selective screening for chronic kidney disease among Vietnamese adults, where the prevalence is 13.1%.
May support targeted CKD screening in Vietnamese adults; hypothesis-generating and requires prospective validation before practice change.
Objectives: Chronic kidney disease (CKD) is associated with disability, low quality of life, and mortality. However, most cases are asymptomatic, often detected incidentally, or only recognized when they have progressed to the later stages with complications. The present study aimed to determine the prevalence of CKD and develop a predictive nomogram for CKD in Vietnamese adults. Methods: This cross-sectional, population-based study involved 533 men and 957 women aged 18 years and older who were screened for CKD. The CKD was diagnosed using the albumin-to-creatinine ratio and/or estimated glomerular filtration rate by the CKD-EPI 2009 equation based on serum creatinine, age, gender, and race (these tests included a baseline measurement and a repeat measurement after 3 months) according to the KDIGO 2012 guideline. We used the Bayesian Model Averaging method to identify the optimal model for predicting CKD. A predictive nomogram was also developed to enable risk prediction. Results: The overall CKD prevalence was 13.1% (95% confidence interval [CI] = 11.6-14.6), with a prevalence of 11.8% (95% CI = 9.1-14.5) in men and 13.8% (95% CI = 11.6-16) in women. The optimal model for predicting CKD included age (odds ratio [OR] per 5-year increase = 1.19; 95% CI = 1.11-1.28), hypertension (OR = 2.08; 95% CI = 1.50-2.89), and diabetes (OR = 1.69; 95% CI = 1.18-2.43). The area under the receiver operating characteristic curve was 0.7, with a 95% CI ranging from 0.65 to 0.73. Conclusions: The CKD is relatively common among Vietnamese adults. A simple model-including age, hypertension, and diabetes-is helpful for the selective screening of CKD in Vietnamese individuals.
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Vo et al. (2025) conducted a cross-sectional in Chronic kidney disease (CKD) (n=1,490). Predictive model (age, hypertension, diabetes) was evaluated on Predictive model performance for CKD (AUC 0.7, 95% CI 0.65-0.73). A predictive model including age, hypertension, and diabetes achieved an area under the curve of 0.7 (95% CI 0.65-0.73) for identifying chronic kidney disease among Vietnamese adults.
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