Key result
A simple 5-variable questionnaire risk score demonstrated fair discrimination (AUC 0.71) for detecting chronic kidney disease, which had a prevalence of 12.76% in a rural Vietnamese population.
Why the study?
Does a simple questionnaire detect individuals at high risk of chronic kidney disease in a rural Vietnamese population?
Cross-Sectional (n=2,037)
Yes
Does a simple questionnaire detect individuals at high risk of chronic kidney disease in a rural Vietnamese population?
Effect estimate: AUC 0.71
A simple 5-variable questionnaire can cost-effectively identify individuals at high risk for chronic kidney disease in rural Vietnam, reducing the need for widespread laboratory screening.
Supports questionnaire-based CKD risk stratification in rural settings; leaves open need for prospective validation before clinical adoption.
The prevalence of chronic kidney disease (CKD) in rural Vietnam is unknown. We wished to determine the prevalence of CKD and determine whether a simple questionnaire was able to detect individuals at high risk of CKD before expensive confirmatory laboratory testing. A cross sectional study was performed. We recruited 2037 participants from 13 communes of Long An province, Vietnam, for CKD screening with urine albumin/creatinine ratio (ACR) measured by immunoturbidimetric method and serum creatinine to estimate glomerular filtration rate (eGFR). CKD was defined as either ACR ≥ 30 mg/g or eGFR MDRD < 60 ml/min/1.73 m 2 . A two page questionnaire with 23 variables was administered to each participant with queries postulated to be correlated with risk of CKD. Of the 2037 participants, 260 (12.76%) were found to have CKD. Five questionnaire variables (age more than 50, measured hypertension, history of diabetes, history of hypertension, and history of a low salt diet) were correlated with CKD, and used to construct a risk score for CKD. CKD is common in Vietnam. Our questionnaire and risk score tool can be used to detect individuals with a higher likelihood of CKD, and who can then be more economically screened with routine laboratory confirmatory tests.
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Tran et al. (2017) conducted a cross-sectional in Chronic kidney disease (n=2,037). 5-variable questionnaire risk score was evaluated on Discrimination of the risk score for detecting chronic kidney disease (AUC 0.71). A simple 5-variable questionnaire risk score demonstrated fair discrimination (AUC 0.71) for detecting chronic kidney disease, which had a prevalence of 12.76% in a rural Vietnamese population.
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