Why the study?
What is the electrical activity and role of the sinus node during atrial fibrillation in isolated rabbit hearts?
Population
Langendorff-perfused rabbit hearts
Comparison
Paroxysms of atrial fibrillation induced by… vs Normal sinus rhythm
Design
Preclinical
Authors
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Preserved sinus automaticity via entrance block may explain rapid post-AF recovery; leaves open human relevance.
What is the electrical activity and role of the sinus node during atrial fibrillation in isolated rabbit hearts?
This study demonstrates that during atrial fibrillation, sinus automaticity is preserved due to sinoatrial entrance block, allowing prompt resumption of sinus rhythm upon AF termination.
Kirchhof et al. (1992) studied this question.
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