Key result
Animal models of arrhythmogenic cardiomyopathies provide valuable insights into the genetic pathways and pathophysiological mechanisms underlying cardiac arrhythmias and sudden cardiac death.
Population
Animal models for arrhythmogenic right ventricular cardiomyopathy, hypertrophic cardiomyopathy and dilated…
Design
Review
Authors
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Supports preclinical mechanistic studies; leaves open clinical translation to human arrhythmogenic cardiomyopathies.
This review summarizes current animal models used to study the genetic pathways and pathogenesis of arrhythmogenic cardiomyopathies, including ARVC, HCM, and DCM.
McCauley et al. (2009) conducted a review in Arrhythmogenic cardiomyopathy. Animal models of arrhythmogenic cardiomyopathies provide valuable insights into the genetic pathways and pathophysiological mechanisms underlying cardiac arrhythmias and sudden cardiac death.
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