Passive Smoking in Adulthood and Cancer Risk1

Overall cancer risk from adult passive smoking has been examined using smoking by spouse as the measure of exposure. Information on smoking by spouse was obtained for 518 cancer cases and 518 noncancer controls. Cancer cases were identified from a hospital-based tumor registry in North Carolina. Cases included all sites except basal cell cancer of the skin and were between the ages of 15 and 59 years at the time of diagnosis. Cancer risk among individuals ever married to smokers was 1.6 times that among those never married to smokers (p less than 0.01). This increased risk was not explained by confounding by individual smoking habits, demographic characteristics, or social class. Elevated risks were seen for several specific cancer sites and were not limited to lung cancer or other "smoking-related" tumors. Risks from passive smoking appeared greater among groups generally at lower cancer risk (females, nonsmokers, and individuals younger than age 50 years), but were not limited to these groups.