What does this research mean for the field?

While the majority of fetal congenital heart defects are detectable during early or mid-gestation ultrasonography, a significant proportion evolve and become detectable only in the third trimester or postnatally. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

July 15, 1997Circulation

Congenital Heart Defects

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Why the study?

Does early transvaginal ultrasound followed by midgestation transabdominal ultrasound alter the detection timing of congenital heart defects compared to midgestation transabdominal ultrasound alone?

Structured PICO

Does early transvaginal ultrasound followed by midgestation transabdominal ultrasound alter the detection timing of congenital heart defects compared to midgestation transabdominal ultrasound alone?

Population

22,050 pregnant women, divided into two groups: 6,924 who had initial transvaginal ultrasonography (TVS) at 13 to 16 weeks' gestation followed by transabdominal ultrasonography (TAS) at 20 to 22 weeks, and 15,126 who had initial TAS at 20 to 22 weeks.

Intervention

Initial transvaginal ultrasonography (TVS) at 13 to 16 weeks' gestation followed by transabdominal ultrasonography (TAS) at 20 to 22 weeks, and subsequent third trimester examination

Comparator

Initial transabdominal ultrasonography (TAS) at 20 to 22 weeks, and subsequent third trimester examination

Outcome

Detection of fetal cardiac anomalies (congenital heart defects) at different stages of pregnancy and postnatallysurrogate

While most fetal cardiac anomalies are detectable early in gestation, a subset evolves later in pregnancy, highlighting the importance of third-trimester echocardiographic evaluation.

Discussion

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Implication

Third-trimester echocardiography may identify evolving fetal CHD missed earlier; leaves open whether routine late screening improves outcomes.

Cite This Study

Yagel et al. (1997) studied this question.

synapsesocial.com/papers/6a1c4834923c8e1e6e9cd5ff https://doi.org/10.1161/01.cir.96.2.550

Topics

Congenital heart disease adults

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Implication

Third-trimester echocardiography may identify evolving fetal CHD missed earlier; leaves open whether routine late screening improves outcomes.

Congenital Heart Defects

Structured PICO

Discussion

Implication

Cite This Study

Topics

Congenital Heart Defects

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

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