What is the clinical evidence from this study?

Study design: Observational. Population: Congenital heart disease (n=43). Intervention: Prenatal ultrasonographic screening. Primary outcome: Overall prenatal detection rate of congenital heart disease.

January 1, 2004Journal of Nippon Medical SchoolOpen Access

Prenatal Diagnosis of Congenital Heart Disease: Clinical Experience and Analysis

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Key result

Routine prenatal ultrasonographic screening detected 34.9% of all major congenital heart diseases, including 27.0% of structural cardiac defects and 83.3% of hemodynamically significant arrhythmias.

Why the study?

What is the prenatal detection rate and clinical outcome of fetuses with congenital heart disease?

Population

19 fetuses prenatally diagnosed with congenital heart disease out of a total of 96 neonates with congenital…

Design

Cohort

Authors

YSYoshio ShimaNippon Medical School Musashi Kosugi Hospital FSFumiko ShindohJapanese Red Cross Katsushika Maternity Hospital MNMizue NakajimaJapanese Red Cross Katsushika Maternity Hospital

Discussion

Member takes

Implication

Low prenatal detection of structural CHD highlights screening gaps; leaves open whether protocol enhancements improve outcomes.

Study Design

Type

Observational (n=43)

Multicenter

Structured PICO

What is the prenatal detection rate and clinical outcome of fetuses with congenital heart disease?

Population

43 fetuses and neonates with major congenital heart disease or hemodynamically significant arrhythmias evaluated over a 5-year period at a single Japanese maternity hospital.

Exposure

Prenatal diagnosis and screening

Outcome

Detection rate of congenital heart disease and fetal/neonatal outcomes (intrauterine deaths, neonatal deaths, infant surgeries)

Limitations

Retrospective study design
Small sample size from a single institution
Standard four-chamber view alone was insufficient to detect certain complex cardiac defects such as CoA, TOF, TGA, and TAPVR
Some complex cardiac defects with normal fetal four-chamber view were difficult to detect prenatally

Cite This Study

Shima et al. (2004) conducted an observational in Congenital heart disease (n=43). Prenatal ultrasonographic screening was evaluated on Overall prenatal detection rate of congenital heart disease. Routine prenatal ultrasonographic screening detected 34.9% of all major congenital heart diseases, including 27.0% of structural cardiac defects and 83.3% of hemodynamically significant arrhythmias.

synapsesocial.com/papers/6a64f3d76b5fc0d0dfa89d6f https://doi.org/10.1272/jnms.71.328

View Full Paper

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Prenatal Diagnosis of Congenital Heart Disease: Clinical Experience and Analysis

Discussion

Member takes

Implication

Study Design

Structured PICO

Limitations

Cite This Study

Prenatal Diagnosis of Congenital Heart Disease: Clinical Experience and Analysis

Discussion

Member takes

Implication

Study Design

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider