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March 1, 1991Archives of Disease in ChildhoodOpen Access

Factors influencing the outcome of congenital heart disease detected prenatally.

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Why the study?

What are the outcomes and factors influencing mortality in prenatally detected congenital heart disease?

Population

222 continuing pregnancies with structural heart disease diagnosed before birth seen over a 10-year period

Design

Cohort

Follow-up

up to >4 years

Authors

GSGurleen SharlandKing's College LondonSLSam LockhartQueen's University BelfastSCSunder ChitaLondon North West Healthcare NHS Trust

Discussion

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Implication

High mortality in fetal CHD warrants cautious prenatal counseling; leaves open prospective studies to refine risk stratification.

Structured PICO

What are the outcomes and factors influencing mortality in prenatally detected congenital heart disease?

P
Population
222 continuing pregnancies with structural heart disease diagnosed before birth seen over a 10-year period
O
Outcome
Mortality (intrauterine, neonatal, and infancy/childhood)hard clinical

Prenatal diagnosis of structural heart disease is associated with high mortality (79%), heavily influenced by the presence of extracardiac anomalies and prenatal cardiac failure.

Cite This Study

Sharland et al. (1991) studied this question.

synapsesocial.com/papers/6a207fcaa25331481ccd429dhttps://doi.org/10.1136/adc.66.3.284

Topics

Congenital heart disease adults
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Echocardiographic Studies of the Human Fetus: Prenatal Diagnosis of Congenital Heart Disease and Cardiac Dysrhythmias1980 · 283 citations
  2. 2Echocardiographic and anatomical correlates in the fetus.1980 · 229 citations
  3. 3Echocardiographic and anatomical correlations in fetal congenital heart disease.1984 · 129 citations
  4. 4Atrioventricular septal defect in prenatal life.1988 · 56 citations
  5. 5Fetal Echocardiography for Evaluation of in Utero Congestive Heart Failure1982 · 245 citations