October 1, 1986Annals of Internal Medicine
The Genetics of Hypertrophic Cardiomyopathy
Population
Patients with hypertrophic cardiomyopathy
Design
Editorial
Authors
Discussion
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Implication
This editorial highlights that hypertrophic cardiomyopathy is genetically transmitted in about one third of cases, typically following an autosomal dominant inheritance pattern.
Key Points
- This editorial addresses the genetic transmission patterns of hypertrophic cardiomyopathy, exploring familial occurrences.
- Reviewed historical cases and reports of hypertrophic cardiomyopathy with a focus on familial patterns.
- Analyzed pedigrees and inheritance characteristics from early clinical studies.
- Hypertrophic cardiomyopathy shows a familial pattern in approximately one third of cases.
- Evidence supports autosomal dominant inheritance of the disease, as noted in several familial instances.
Structured PICO
P
Population
Patients with hypertrophic cardiomyopathy
This editorial highlights that hypertrophic cardiomyopathy is genetically transmitted in about one third of cases, typically following an autosomal dominant inheritance pattern.
Cite This Study
Maron et al. (1986) studied this question.