Key result
Acute increases in extravascular pressure via forearm compressions elicited significant rapid vasodilatation (peak DeltaFVC ~155% at 200 mmHg for 2 s), peaking within 1-2 cardiac cycles.
Why the study?
Does mechanical deformation of forearm blood vessels via acute increases in extravascular pressure elicit rapid vasodilatation in healthy adults?
Population
Healthy adults
Comparison
Mechanical deformation of forearm blood vessels… vs Different compression protocols
Design
Other
Authors
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Highlights mechanical deformation in rapid skeletal muscle vasodilatation; extends mechanistic understanding but leaves open clinical relevance.
Does mechanical deformation of forearm blood vessels via acute increases in extravascular pressure elicit rapid vasodilatation in healthy adults?
Mechanical deformation of blood vessels via acute increases in extravascular pressure contributes significantly to the immediate contraction-induced rapid vasodilatation observed in human skeletal muscle.
Kirby et al. (2007) studied Healthy adults. Whole forearm compressions and isometric muscle contractions was evaluated on Forearm vascular conductance (FVC) responses. Acute increases in extravascular pressure via forearm compressions elicited significant rapid vasodilatation (peak DeltaFVC ~155% at 200 mmHg for 2 s), peaking within 1-2 cardiac cycles.
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