Key result
Transcatheter ASD closure in patients ≥40 years resulted in new atrial fibrillation in 6% of those without prior arrhythmia, while only 9% with persistent AF achieved sinus rhythm.
Why the study?
Does transcatheter ASD closure restore or maintain sinus rhythm in patients ≥40 years of age with or without prior atrial arrhythmias?
Population
159 patients ≥40 years of age undergoing transcatheter closure of secundum atrial septal defects…
Design
Cohort
Follow-up
median 3.6 years (range 6 months-10.9 years)
Authors
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ASD closure warrants arrhythmia caution in adults ≥40; observational data leave open its net effect versus medical management.
Observational (n=159)
Does transcatheter ASD closure restore or maintain sinus rhythm in patients ≥40 years of age with or without prior atrial arrhythmias?
Transcatheter ASD closure in patients ≥40 years old does not reliably eliminate atrial arrhythmias, especially in those with persistent AF, and new-onset AF still occurs in a small percentage of patients.
Duong et al. (2016) conducted an observational in Secundum atrial septal defect (n=159). Transcatheter closure of secundum atrial septal defects vs. Comparison by prior arrhythmia status was evaluated on Atrial arrhythmia status on follow-up. Transcatheter ASD closure in patients ≥40 years resulted in new atrial fibrillation in 6% of those without prior arrhythmia, while only 9% with persistent AF achieved sinus rhythm.
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