What does this research mean for the field?

Current guidelines for heparin therapy are based on clinically irrelevant experimental work, and adequate anticoagulation should be assessed by clinical response rather than inaccurate laboratory tests, requiring high initial doses to control clotting. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.CHALLENGES_CONSENSUS.

December 1, 1996Cardiovascular Surgery

Heparin — Controversies and Misconceptions

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Design

Review

Authors

FBF. William BlaisdellUniversity of California Davis Medical Center

Discussion

Member takes

Implication

Standard heparin monitoring may not reflect anticoagulation adequacy; challenges consensus yet remains hypothesis-generating.

Structured PICO

Intervention

Heparin therapy

This review challenges traditional heparin monitoring and dosing guidelines, suggesting clinical response is a better indicator of adequate anticoagulation than current laboratory tests.

Cite This Study

F. William Blaisdell (1996) studied this question.

synapsesocial.com/papers/6a1c59f34ebd09f3dfa9bd2f https://doi.org/10.1177/096721099600400603

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Heparin — Controversies and Misconceptions

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Heparin — Controversies and Misconceptions

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider