What question did this study set out to answer?

The aim is to establish guidelines for effective heparin therapy in venous thromboembolic disease based on existing clinical observations.

January 9, 1967JAMA

Some Guidelines for Heparin Therapy of Venous Thromboembolic Disease

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Why the study?

How should heparin be administered for the treatment of venous thromboembolic disease?

Population

Patients with venous thromboembolic disease

Design

Guideline

Authors

VGVictor GurewichHarvard University

Discussion

Member takes

Implication

Standardized adequate heparin dosing is required for effective VTE treatment; extends observational evidence into clinical guidelines.

Key Points

The aim is to establish guidelines for effective heparin therapy in venous thromboembolic disease based on existing clinical observations.
Review of existing literature on heparin administration practices
Analysis of variability in dosage, route, and duration across institutions
Formulation of guidelines based on clinical and experimental evidence.
Lack of standardization contributes to confusion and variability in anticoagulant effectiveness.
Different institutions show significant discrepancies in treatment approaches, increasing the risk of complications.
Insufficient attention to dosage may lead to diminished clinical outcomes with heparin therapy.

Structured PICO

How should heparin be administered for the treatment of venous thromboembolic disease?

Population

Patients with venous thromboembolic disease

Intervention

Heparin therapy

This paper provides historical guidelines for the administration of heparin in venous thromboembolic disease, highlighting the need for standardized dosing.

Limitations

Paucity of well-controlled clinical trials

Cite This Study

Victor Gurewich (1967) studied this question.

synapsesocial.com/papers/6a2304375fbd55e814a9686c https://doi.org/10.1001/jama.1967.03120020110021

View Full Paper

Ask AI

Bookmark

Some Guidelines for Heparin Therapy of Venous Thromboembolic Disease

Discussion

Member takes

Implication

Key Points

Structured PICO

Limitations

Cite This Study

Some Guidelines for Heparin Therapy of Venous Thromboembolic Disease

Discussion

Member takes

Implication

Key Points

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider