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April 11, 1977JAMA

Isolated Aortic Valve Replacement in Patients Older Than 65 Years

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Population

196 patients older than 65 years undergoing isolated aortic valve replacement, with 84% in NYHA functional…

Design

Cohort

Follow-up

5 years

Authors

JCJack G. CopelandHeart Failure / Cardiomyopathy

Discussion

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Implication

Supports AVR consideration in select elderly patients; leaves open need for randomized trials to confirm benefits in current practice.

Key Points

  • Assess outcomes and risks associated with isolated aortic valve replacement in patients age 65 and older.
  • Analyzed 196 cases of isolated aortic valve replacements
  • Evaluated preoperative functional status using NYHA classification
  • Recorded postoperative mortality and complications.
  • Operative mortality was 12% overall, 9% for elective cases.
  • Five-year survival probability was 55% for all patients, 61% for those discharged.
  • 16% of discharged patients experienced embolic strokes, causing disability in 9%.

Structured PICO

P
Population
196 patients older than 65 years undergoing isolated aortic valve replacement, with 84% in NYHA functional class III or IV preoperatively
I
Intervention
Isolated aortic valve replacement
O
Outcome
Operative mortality and five-year survivalhard clinical

Isolated aortic valve replacement in patients older than 65 years carries a reasonable operative risk and results in satisfactory long-term survival and functional improvement.

Cite This Study

Jack G. Copeland (1977) studied this question.

synapsesocial.com/papers/6a1c5a701567d2fc4d5ffa43https://doi.org/10.1001/jama.1977.03270420046014
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