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November 1, 1963Journal of Applied Physiology149 citations

Relationship of radius to pressure along the aorta in living dogs

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Why the study?

What is the relationship between radius and pressure along the aorta in living dogs?

Population

30 living dogs

Design

Preclinical

Authors

DPDali J. PatelFFFLAVIO M. DE FREITASJGJoseph C. Greenfield

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Overview

Should not guide human aortic assessment; leaves open translation of segmental elasticity gradients to clinical models.

Structured PICO

What is the relationship between radius and pressure along the aorta in living dogs?

P
Population
30 living dogs
I
Intervention
Measurement of instantaneous pressure-radius relationship using an electrical caliper and relative dimensions using Jeltrate casts
O
Outcome
Instantaneous pressure-radius relationship (ΔR/ΔP), mean radius, and pressure-strain elastic modulus (Ep) along the aortasurrogate

This foundational physiological study demonstrates that aortic elasticity decreases and radius decreases progressively from the ascending aorta to the bifurcation in living dogs.

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Cite This Study

Patel et al. (1963) studied this question.

synapsesocial.com/papers/6a1c5ba1ea84844e355fc8a8https://doi.org/10.1152/jappl.1963.18.6.1111
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