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January 1, 1960Journal of Applied Physiology

Mechanical properties and dimensions of the major pulmonary arteries

Dali J. Patel Donald P. Schilder Alexander J. Mallos

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Structured PICO

P

Population

18 living thoracotomized dogs

I

Intervention

Norepinephrine administration

C

Comparator

Control observations over a range of pressures induced by rapid, right heart dextran-infusion

O

Outcome

Relationship between instantaneous distending pressure and diameter of the pulmonary artery (ratio of change in radius to pulse pressure)surrogate

Implication

Norepinephrine administration significantly decreases the distensibility of the pulmonary artery in a canine model.

Discussion

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Cite This Study

Patel et al. (1960) studied this question.

synapsesocial.com/papers/6a9081d9e02ba012352dc45a https://doi.org/10.1152/jappl.1960.15.1.92

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Relationship of aortic pressure and diameter in the dogpreclinical · 1961 · 72 citations
2Pressure dependence of the mechanical properties of arteries in vivopreclinical · 1975 · 98 citations
3Mechanical function of the main pulmonary arterypreclinical · 1962 · 40 citations
4Pressure-diameter relations of the in vivo aortapreclinical · 1962 · 14 citations
5Response of the Main Pulmonary Artery of Dogs to Neuronally Released Versus Blood-Borne Norepinephrinepreclinical · 1970 · 46 citations