Population
10 living anesthetized dogs
Design
Preclinical
Authors
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Preclinical aortic strain data should not change clinical practice; extends biomechanical hypotheses but leaves open human validation.
This preclinical study demonstrates that longitudinal and circumferential strains in the ascending aorta are large and influenced by forces from heart contraction beyond just intravascular pressure.
Patel et al. (1964) studied this question.