Key result
Aortic wall stress and strain-energy density peak at the endothelium and drop sharply across the inner third.
Why the study?
A method was needed to determine the distribution of circumferential, longitudinal, and radial stresses and strain-energy density through the wall thickness of canine aortic segments under physiological loading.
Population
Aortic segments from 13 dogs
Comparison
Different intraluminal pressures and longitudinal forces
Design
In vitro study applying nonlinear theory of large deformation without thin-wall assumption
Authors
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May inform vascular biomechanics models; leaves open in vivo human translation.
Vaishnav et al. (1973) studied this question. Varying intraluminal pressure and longitudinal force was evaluated on Distribution of circumferential, longitudinal, and radial stress and strain-energy density. In canine aortic segments, stresses and strain-energy density were largest at the endothelial surface and decreased toward the adventitial surface, with the decrease most marked in the inner third.
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