What does this research mean for the field?

Calmodulin (CaM) regulates the plasma membrane calcium pump and likely functions as a permanent subunit of the Ca2+ pump ATPase in vivo due to high occupancy of pump sites. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

December 1, 1980Annals of the New York Academy of Sciences

Calmodulin and the Plasma Membrane Calcium Piimp*

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Population

Red blood cells (RBCs) and isolated RBC membranes

Design

Preclinical

Authors

FVFrank F. VincenziUniversity of Washington THThomas R. HindsUniversity of Washington BRBeat U. RaessUniversity of Evansville

Discussion

Member takes

Implication

Supports CaM as RBC Ca2+ pump subunit; extends regulatory data but leaves open human translation.

Structured PICO

Population

Red blood cells (RBCs) and isolated RBC membranes

Intervention

Calmodulin (CaM) and Ca2+ loading

Outcome

Regulation and activation of the plasma membrane (Ca2+ + Mg2+)-ATPasesurrogate

Calmodulin likely functions as an integral subunit of the plasma membrane calcium pump ATPase in red blood cells in vivo.

Cite This Study

Vincenzi et al. (1980) studied this question.

synapsesocial.com/papers/6a1c66531d5b34640aa147df https://doi.org/10.1111/j.1749-6632.1980.tb29614.x

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Calmodulin and the Plasma Membrane Calcium Piimp*

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Calmodulin and the Plasma Membrane Calcium Piimp*

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider