Key result
Persistent intramyocardial inflammation is linked to ~44% worse global systolic longitudinal strain at follow-up.
Why the study?
Does speckle tracking echocardiography correlate with intramyocardial inflammation in patients with acute myocarditis?
Cohort (n=25)
No
Does speckle tracking echocardiography correlate with intramyocardial inflammation in patients with acute myocarditis?
Absolute Event Rate: -9.4% vs -16.8%
p-value: p=<0.0001
Speckle tracking echocardiography parameters (longitudinal strain and strain rate) correlate significantly with biopsy-proven intramyocardial inflammation, offering a potential non-invasive tool to monitor myocarditis.
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Impaired strain may signal persistent inflammation in myocarditis; supports speckle tracking correlation but leaves open prospective validation before clinical use.
Escher et al. (2013) conducted a cohort in Acute myocarditis and inflammatory cardiomyopathy (n=25). Persistent intramyocardial inflammation vs. No persistent intramyocardial inflammation was evaluated on Global systolic longitudinal strain (LS) at follow-up (p=<0.0001). At 6.2 months follow-up, global systolic longitudinal strain was significantly impaired in patients with persistent intramyocardial inflammation compared to those without inflammation (-9.4% vs -16.8%, p<0.0001).
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