Key result
Acute myocarditis with preserved LVEF shows ~8% lower left atrial reservoir function versus healthy controls.
Why the study?
CMR feature tracking data suggest left ventricular and left atrial impairment in acute myocarditis, prompting investigation of the diagnostic value of speckle tracking echocardiography of both chambers in patients with normal LVEF.
Does speckle tracking echocardiography detect impaired left atrial and left ventricular strain in patients with acute myocarditis and preserved LVEF compared to healthy controls?
Case-Control (n=50)
No
Does speckle tracking echocardiography detect impaired left atrial and left ventricular strain in patients with acute myocarditis and preserved LVEF compared to healthy controls?
Absolute Event Rate: 47.6% vs 55.5%
p-value: p=0.013
Echocardiographic left atrial strain analysis reveals impaired LA reservoir and conduit function in patients with acute myocarditis despite preserved LVEF, indicating subclinical diastolic dysfunction.
May indicate subclinical diastolic dysfunction in acute myocarditis with preserved LVEF; hypothesis-generating, requires prospective validation.
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Meindl et al. (2023) conducted a case-control in Acute myocarditis with preserved systolic left ventricular function (n=50). Acute myocarditis vs. Healthy controls was evaluated on Left atrial reservoir function (p=0.013). In patients with acute myocarditis and preserved LVEF, left atrial reservoir function was significantly impaired compared to healthy controls (47.6% vs. 55.5%, p=0.013).
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