Key result
CMR-derived LV global longitudinal strain independently predicted major adverse cardiovascular events in patients with acute myocarditis (HR 1.07, P=0.02).
Why the study?
CMR late gadolinium enhancement and LV ejection fraction have limited predictive value for heart failure or life-threatening arrhythmias in acute myocarditis, whereas CMR feature-tracking strain may improve risk stratification.
Does CMR-derived myocardial strain analysis predict major adverse cardiovascular events in patients with acute myocarditis?
Population
162 patients with CMR-proven acute myocarditis
Comparison
Prognostic value of LV, right ventricular, and left atrial strain parameters
Design
Multicenter retrospective study
Follow-up
5.5 (2.2–8.3) years
Authors
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LV strain independently predicted MACE beyond LVEF and LGE in acute myocarditis; hypothesis-generating for risk stratification, should not yet change practice.
Cohort (n=162)
Yes
Does CMR-derived myocardial strain analysis predict major adverse cardiovascular events in patients with acute myocarditis?
Hazard Ratio: 1.07
p-value: p=0.02
Vos et al. (2022) conducted a cohort in Acute myocarditis (n=162). CMR-derived LV strain analysis was evaluated on Major adverse cardiovascular events (all-cause mortality, heart transplantation, heart failure hospitalizations, and life threatening arrhythmias) (HR 1.07, p=0.02). CMR-derived LV global longitudinal strain independently predicted major adverse cardiovascular events in patients with acute myocarditis (HR 1.07, P=0.02).
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