Key result
Left atrial reservoir strain derived from cardiac magnetic resonance imaging independently predicted composite adverse cardiac events in patients with acute myocarditis, with a 10% risk reduction per 1% increase in strain (HR 0.90).
Why the study?
Left atrial strain is an emerging prognostic marker in cardiac diseases, but its prognostic value in acute myocarditis remains unclear.
Does CMR-derived left atrial strain predict adverse clinical outcomes in patients with acute myocarditis?
Population
47 consecutive patients with acute myocarditis who underwent CMR
Comparison
Prognostic value of feature-tracked CMR-derived LA strain parameters
Design
Retrospective cohort study
Follow-up
Median 37 months
Authors
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May inform prognosis in acute myocarditis; hypothesis-generating and requires prospective validation.
Cohort (n=47)
No
Does CMR-derived left atrial strain predict adverse clinical outcomes in patients with acute myocarditis?
Hazard Ratio: 0.9 (95% CI 0.84–0.96)
p-value: p=0.002
CMR-derived left atrial reservoir and conduit strains are independent predictors of adverse clinical outcomes in patients with acute myocarditis.
Lee et al. (2023) conducted a cohort in Acute myocarditis (n=47). Left atrial strain vs. Per 1% increase was evaluated on Composite of cardiac death, heart transplantation, implantable cardioverter-defibrillator or pacemaker implantation, rehospitalization following a cardiac event, atrial fibrillation, or embolic stroke (HR 0.90, 95% CI 0.84-0.96, p=0.002). Left atrial reservoir strain derived from cardiac magnetic resonance imaging independently predicted composite adverse cardiac events in patients with acute myocarditis, with a 10% risk reduction per 1% increase in strain (HR 0.90).
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