Why the study?
What is the primary effect of vagus nerve and stellate ganglion stimulation on the coronary vasculature?
Population
Paced, nonpaced beating, and fibrillating hearts undergoing constant pressure perfusion of the left coronary…
Design
Preclinical
Authors
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Caution against clinical translation from this animal model; extends agonist data but leaves open human coronary responses to vagal and sympathetic stimulation.
What is the primary effect of vagus nerve and stellate ganglion stimulation on the coronary vasculature?
The primary effect of vagus nerve stimulation on the coronary vasculature is vasodilation, while stellate ganglion stimulation causes initial constriction followed by secondary metabolic vasodilation.
Berne et al. (1965) studied this question.
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