Why the study?
Does stimulation of the stellate ganglia affect coronary blood flow?
Does stimulation of the stellate ganglia affect coronary blood flow?
This study investigates the physiological effect of sympathetic nerve (stellate ganglia) stimulation on coronary blood flow.
Answers are grounded in this paper and cite their sources.
Stellate ganglia stimulation may modulate coronary flow; leaves open clinical relevance in humans.
Nervous control of the coronary circulation has long been studied, but many problems remain to be further investigated. In general, the coronary blood flow increases by the sympathetic nerve stimulation, and decreases by the vagal nerve stimulation. But, the stimulation of the sympathetic or vagal nerve to the heart produces significant changes in hemodynamic and metabolic factors, such as blood pressure, heart rate, vigor of contraction, ratio of systole/diastole, cardiac output, extravascular compression, massging action of the heart, oxygen consumption and metabolites. Therefore, it can not be simply concluded that the sympathetic nerve causes active coronary vasodilatation, while the vagal nerve causes active coronary vasoconstriction.In the present paper, the effects of the stimulation of the stellate ganglia upon the coronary blood flow were reported (in the next paper, the stimulation of the vagal nerve is to be reported). Experimental methods were same as already described in Part I of this study.
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Kunitake Hashiba (1958) studied this question.
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