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Objective: Transplantation of human embryonic dopaminergic progenitors within the striata of PD patients has provided encouraging results, but ethical concerns and tissue availability limit this approach. The use of mesenchymal stem cells (MSCs) provides a readily available source of cells, as they are derived from adult tissue. This in vitro study explored the use of MSCs as a cell source for DA neuronal induction utilizing a single adenovirus.
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Welchko et al. (2018) studied this question.
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