Key result
Catheter ablation of ventricular tachycardia after myocardial infarction achieved similar acute success rates for stable (69%) and unstable (64%) VTs (p=0.42).
Why the study?
Does a targeted catheter ablation strategy yield similar acute success and recurrence rates for stable versus unstable ventricular tachycardias in patients with previous myocardial infarction?
Cohort (n=30)
Does a targeted catheter ablation strategy yield similar acute success and recurrence rates for stable versus unstable ventricular tachycardias in patients with previous myocardial infarction?
Absolute Event Rate: 69% vs 64%
p-value: p=0.42
Catheter ablation targeting only previously documented VTs and those with similar or longer cycle lengths yields comparable acute success and recurrence rates for both stable and unstable VTs in post-MI patients.
Supports ablation of unstable post-MI VT; leaves open need for randomized confirmation of outcomes.
OBJECTIVE: Catheter ablation of ventricular tachycardia (VT) after myocardial infarction (MI) can be complex and time-consuming. We only targeted the previously documented VTs and those with similar or longer cycle lengths. METHODS: 30 patients with VTs after MI were included in the study. Voltage mapping was performed using an electro-anatomic mapping system (CARTOT). Stable VTs were mapped during tachycardia and unstable VTs during sinus rhythm. RESULTS: Clinical VTs were stable in 16 (53%) and unstable in 14 (47%) patients, and ablation was successful in 11 (69%) and 9 patients (64%), respectively (p = 0.42). During follow-up (14 +/- 6 months), 4 patients (25%) treated for stable and 6 (43%) for unstable VTs had recurrences (p = 0.82); ablation was successful in none and 2 (33%) of them, respectively. Non-target VTs were inducible in 11 (55%) of 20 patients after successful ablation and non-inducible in 9 (45%). During follow-up, inducibility of non-target VTs did not predict recurrences (9 vs. 11%, p = 0.88). CONCLUSIONS: Catheter ablation of VTs after MI can be successfully performed. Acute success rates seem to be similar for stable and unstable VTs. VTs faster than those documented clinically exert a minor effect on VT recurrences during follow-up.
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Ventura et al. (2007) conducted a cohort in Ventricular tachycardia after myocardial infarction (n=30). Catheter ablation vs. Stable vs unstable VTs was evaluated on Acute ablation success (p=0.42). Catheter ablation of ventricular tachycardia after myocardial infarction achieved similar acute success rates for stable (69%) and unstable (64%) VTs (p=0.42).
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