Key result
In patients with suspected acute appendicitis, raised white blood cell count demonstrated 80% sensitivity and 67% specificity, while abdominal ultrasonography had a diagnostic accuracy of only 58.2%.
Why the study?
What is the diagnostic accuracy of clinical scores, laboratory tests, and radiological imaging for acute appendicitis in patients with right iliac fossa pain?
Population
200 patients with acute right iliac fossa pain, including both genders and all ages
Comparison
Diagnostic evaluation using Alvarado score, WBC… vs Histopathological findings of appendix specimen
Design
Cross-sectional
Authors
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WBC count may aid triage in suspected appendicitis; leaves open need for validated imaging strategies in prospective cohorts.
Observational (n=160)
No
What is the diagnostic accuracy of clinical scores, laboratory tests, and radiological imaging for acute appendicitis in patients with right iliac fossa pain?
Absolute Event Rate: 80% vs 67%
The Alvarado scoring method and WBC count are helpful in the decision-making process for operative intervention in acute appendicitis, whereas ultrasonography showed limited accuracy.
Momin et al. (2015) conducted an observational in Acute appendicitis (n=160). Diagnostic modalities (WBC count, CRP, Alvorado score, Ultrasonography) vs. Histopathology (gold standard) was evaluated on Sensitivity and specificity of raised white blood cell count. In patients with suspected acute appendicitis, raised white blood cell count demonstrated 80% sensitivity and 67% specificity, while abdominal ultrasonography had a diagnostic accuracy of only 58.2%.
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