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February 1, 1987Biochemistry

Prothrombin Tokushima, a replacement of arginine-418 by tryptophan that impairs the fibrinogen clotting activity of derived thrombin Tokushima

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Authors

TMToshiyuki MiyataNational Cerebral and Cardiovascular CenterTMTakashi MoritaChubu UniversityTIT Inomoto

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Miyata et al. (1987) studied this question.

synapsesocial.com/papers/6a1c9589973ffece4bc403d1https://doi.org/10.1021/bi00378a020
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  4. 4Computer-generated models of blood coagulation factor Xa, factor IXa, and thrombin based upon structural homology with other serine proteases.1982 · 223 citations
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