Key result
Aliskiren and other renin-angiotensin-aldosterone system inhibitors are promising for managing hypertension and end-organ protection, though long-term mortality data are currently lacking.
Why the study?
Do RAAS inhibitors, including aliskiren, provide effective blood pressure control and end-organ protection in elderly patients with hypertension compared to older agents?
Population
Elderly patients with hypertension
Comparison
Aliskiren and other renin-angiotensin-aldosterone… vs Beta-blockers and thiazide diuretics
Design
Review
Authors
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May support RAAS inhibitor use in elderly hypertension; leaves open long-term mortality trials for aliskiren.
Do RAAS inhibitors, including aliskiren, provide effective blood pressure control and end-organ protection in elderly patients with hypertension compared to older agents?
RAAS inhibitors are established as safe and effective first-line treatments for hypertension, but long-term mortality data for direct renin inhibitors like aliskiren are still needed.
Karl Andersen (2009) conducted a review in Hypertension. Aliskiren was evaluated. Aliskiren and other renin-angiotensin-aldosterone system inhibitors are promising for managing hypertension and end-organ protection, though long-term mortality data are currently lacking.
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