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October 8, 2021ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam)122 citationsOpen Access

FlyAtlas 2 in 2022: enhancements to the Drosophila melanogaster expression atlas

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SKSue Ann KrauseGOGayle OverendJDJulian A. T. Dow

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Abstract

FlyAtlas 2 (flyatlas2.org) is a database and web application for studying the expression of the genes of Drosophila melanogaster in different tissues of adults and larvae. It is based on RNA-Seq data, and incorporates both genes encoding proteins and microRNAs. We have now completed the population of the database with 13 tissues from both male and female adults, five sex-specific tissues, and eight larval tissues. Larval garland cell nephrocytes have also been included. Major enhancements have been made to the application. First, a facility has been added for a 'Profile' search for genes with a similar pattern of tissue expression as a query gene. This may help establish the function of genes for which this is currently unknown. Second, a facility has been added dedicated to the larval midgut, where the difference in gene expression in the five regions of different pH can be explored. A variety of further improvements to the interface are described.

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Krause et al. (2021) studied this question.

synapsesocial.com/papers/6a1cafb25b2142ad731d928ehttps://doi.org/10.1093/nar/gkab971
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