Why the study?
Does moderately reduced LVEF worsen outcomes after mitral valve replacement in patients with mitral stenosis?
Does moderately reduced LVEF worsen outcomes after mitral valve replacement in patients with mitral stenosis?
Moderate depression of LVEF in patients with mitral stenosis increases the risk of heart failure after mitral valve replacement but does not significantly impact overall mortality, suggesting it should not be a contraindication to surgery.
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Moderately reduced LVEF was associated with higher postoperative HF but similar mortality after mitral valve replacement; leaves open effects on surgical risk stratification.
Mangoni et al. (2002) studied this question.
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