What does this research mean for the field?

High-intensity interval training (HIIT) improves cardiorespiratory fitness and endothelial function in patients with type 2 diabetes, and may be superior to moderate-intensity continuous training (MICT) in enhancing these parameters. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

April 20, 2023World Journal of CardiologyOpen Access

Effectiveness of high intensity interval training on cardiorespiratory fitness and endothelial function in type 2 diabetes: A systematic review

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Why the study?

The beneficial effects of high intensity interval training on cardiorespiratory fitness and endothelial function in patients with T2DM remained under investigation, with a limited number of studies.

Does high-intensity interval training improve cardiorespiratory fitness and endothelial function in patients with type 2 diabetes mellitus compared to moderate-intensity continuous training or usual care?

Population

Patients with T2DM across 12 studies

Comparison

HIIT vs MICT, strength endurance, or control

Design

Systematic review

Authors

CKChristos KourekNational and Kapodistrian University of Athens EKEleftherios KaratzanosNational and Kapodistrian University of Athens VRVasiliki RaidouNational and Kapodistrian University of Athens

Discussion

Member takes

Implication

HIIT supports updated exercise guidance for T2DM; extends superiority evidence from general CVD populations to diabetes.

Structured PICO

Population

12 RCTs pooling 661 patients with type 2 diabetes mellitus (406 males, 255 females), mean age 38-65 years, mean time since diagnosis 1.79-21.1 years, mean HbA1c 6.4-7.5%, BMI 26.5-33.9 kg/m2.

Intervention

High-intensity interval training (HIIT) for 8 weeks to 12 months, 2 to 5 times weekly.

Comparator

Moderate-intensity continuous training (MICT), strength endurance, or usual care (control group).

Outcome

Cardiorespiratory fitness assessed by peak oxygen uptake (peak VO2).surrogate

High-intensity interval training improves cardiorespiratory fitness and endothelial function in patients with type 2 diabetes, potentially to a greater extent than moderate-intensity continuous training.

Limitations

Heterogeneity of the study samples (different mean age, duration since diagnosis, functional capacity at baseline)
Lack of adjustment for multiple comparisons and potential confounders in some studies
Potential inclusion bias (patients who undertook intervention may have been more motivated)

Cite This Study

Kourek et al. (2023) studied this question.

synapsesocial.com/papers/6a1cd98d5a7763abe789d192 https://doi.org/10.4330/wjc.v15.i4.184

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Effectiveness of high intensity interval training on cardiorespiratory fitness and endothelial function in type 2 diabetes: A systematic review

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Effectiveness of high intensity interval training on cardiorespiratory fitness and endothelial function in type 2 diabetes: A systematic review

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

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