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December 1, 1996Journal of the American College of CardiologyOpen Access

Seasonal Pattern of Acute Myocardial Infarction in the National Registry of Myocardial Infarction

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Authors

JOJoseph P. OrnatoMPMary Ann PeberdyNCNisha C. Chandra

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Overview

Registry study reveals increased acute myocardial infarction admissions during winter and spring, indicating that external environmental factors trigger cardiovascular events.

Key Points

  • To determine whether hospital admission rates for acute myocardial infarction demonstrate seasonal variation in a large, prospective national registry.
  • Analyzed seasonal mean cases of acute myocardial infarction submitted to the National Registry of Myocardial Infarction (NRMI) by 138 high-volume core hospitals over a 3-year period (December 21, 1990 to December 20, 1993; N=83,541).
  • Adjusted case counts for the number of days in each season and evaluated trends using general linear modeling and analysis of variance.
  • Core hospitals entered approximately 10% more acute myocardial infarction cases during winter and spring compared to summer (p < 0.05).
  • The seasonal pattern was consistent across northern and southern states, men and women, age groups (<70 vs. ≥70 years), and infarct presentations (Q-wave vs. non-Q-wave).

Cite This Study

Ornato et al. (1996) studied this question.

synapsesocial.com/papers/6a1ce4f06552df3dce1dba4ahttps://doi.org/10.1016/s0735-1097(96)00411-1
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Also Consider

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  1. 1Circadian Variation in the Frequency of Onset of Acute Myocardial Infarction1985 · 1,894 citations
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