Why the study?
Do cardiovascular risk factors and atheromatous disease alter the central-to-peripheral pulse pressure ratio compared to healthy individuals?
Do cardiovascular risk factors and atheromatous disease alter the central-to-peripheral pulse pressure ratio compared to healthy individuals?
Cardiovascular risk factors significantly alter the pulse pressure ratio, demonstrating that central aortic pressure cannot be reliably inferred from peripheral brachial pressure alone.
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Risk factors blunt pulse pressure amplification, so brachial readings may mask aortic hypertension; hypothesis-generating for central BP-guided risk stratification.
McEniery et al. (2008) studied this question.
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