Primary cardiac lymphoma, though rare and typically seen in immunocompromised patients, can occur in immunocompetent individuals and responds well to R-CHOP chemotherapy.
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May support R-CHOP responsiveness in primary cardiac lymphoma; hypothesis-generating and requires prospective validation.
Cardiac lymphoma is a rare neoplasm involving heart, pericardium or both, usually seen in immunocompromised patients. We report a 61-year-old male presenting with worsening shortness of breath and 20-pound weight loss. Investigations showed right-sided tumor with interatrial septal wall perforation and left atrial expansion. The diagnosis was confirmed with mediastinal mass biopsy. After receiving the appropriate treatment, there was a steady improvement clinically and on the transesophageal echocardiography.
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Ajam et al. (2021) studied this question.
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