Why the study?
This study investigated abnormal pupillary light reflex in patients with early diabetes mellitus without retinopathy using a custom-made noninvasive portable pupilometer.
Does pupillary light reflex measurement using a custom pupilometer detect abnormal autonomic neuropathy in patients with early diabetes mellitus compared to healthy individuals?
Does pupillary light reflex measurement using a custom pupilometer detect abnormal autonomic neuropathy in patients with early diabetes mellitus compared to healthy individuals?
Pupillary light reflex indices (DRP, MRV, ARV) measured by a portable pupilometer can detect early autonomic neuropathy in patients with diabetes without retinopathy.
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May support early autonomic neuropathy detection in DM via portable pupilometry; hypothesis-generating and requires prospective validation.
Yan et al. (2021) studied this question.
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