Why the study?
Spatial localization of ventricular abnormal potentials can identify ablation targets in substrate-guided mapping, motivating an automatic approach for their reliable detection in intracardiac electrograms.
Does an automatic machine learning approach accurately detect ventricular abnormal potentials in intracardiac electrograms compared to expert annotation?
Does an automatic machine learning approach accurately detect ventricular abnormal potentials in intracardiac electrograms compared to expert annotation?
An automatic machine learning approach can accurately detect ventricular abnormal potentials in intracardiac electrograms, potentially aiding in substrate-guided mapping and ablation.
Ventricular abnormal potentials are low-amplitude electrical signals that appear in intracardiac electrograms during a QRS or with an unpredictable delay with respect to it. Their spatial localization can be exploited by cardiologists for the identification of the ablation targets in substrate-guided mapping and ablation procedures. In this work, an automatic approach for a reliable detection of such potentials in intracardiac electrograms is proposed.To this aim, 86 intracardiac electrograms from five patients with post-ischemic ventricular tachycardia, acquired by the CARTO3 System, were retrospectively annotated by an expert cardiologist, to be used for a supervised classifier training and test.The automatic detection was based on a non-linear denoising followed by a time-scale decomposition based on the continuous wavelet transform. Then, different morphological features were extracted from both the time-scale domain and the time domain, and used to feed a support vector machine trained to discriminate between physiological and abnormal potentials. The recognition accuracy exceeded 93%, paving the way to further developments and more extensive studies.
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Baldazzi et al. (2019) studied this question.
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