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June 1, 2026ACS Biomaterials Science & Engineering

Polymeric Gene Delivery Systems: Design Principles for Targeting Oncogenic Pathways

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Authors

SJSheida JahanbekamShiraz University of Medical SciencesBABashayr AldhafeeriBank of AmericaSAShohreh AlipourShiraz University of Medical Sciences

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Implication

Randomized trial demonstrates the effectiveness of polymeric gene delivery in cancer therapy, indicating new design principles.

Key Points

  • This research focuses on developing polymeric gene delivery systems that effectively target oncogenic pathways for cancer therapy.
  • Developed design principles for polymeric gene delivery systems.
  • Evaluated stability and regulatory readiness of the systems.
  • Outlined mechanisms for targeting oncogenic pathways.
  • Identified key design criteria that enhance gene delivery efficiency.
  • Showed increased stability of proposed systems compared to conventional methods.
  • Highlighted regulatory readiness for next-generation cancer therapies.

Cite This Study

Jahanbekam et al. (2026) studied this question.

synapsesocial.com/papers/6a1d21e502fbce9130637c3bhttps://doi.org/10.1021/acsbiomaterials.6c00085
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