Why the study?
Hypertension leads to cardiovascular complications, and prehypertension is a precursor of Stage-I hypertension, motivating assessment of sympathetic activity across these states.
Does sympathetic activity differ among normotensive, prehypertensive, and hypertensive individuals?
Does sympathetic activity differ among normotensive, prehypertensive, and hypertensive individuals?
Autonomic function tests reveal sympathetic overactivity in prehypertension and dysfunction in hypertension, highlighting their potential utility in early risk prediction.
Introduction: Hypertension is a major health hazard which at a later stage might lead onto various cardiovascular complications. Prehypertension is a precursor of Stage-I hypertension. Thus, the present study was done to assess the sympathetic activity in normotensive, prehypertensive and hypertensive individuals. Aims and Objectives: To compare the differences in sympathetic activity in normotensive, prehypertensive and hypertensive individuals. Materials and Methods: The study was conducted on 30 normotensive, 30 prehypertensive and 30 hypertensive subjects. Autonomic function tests were recorded using the instrument Physiopac-PP4, Medicaid system, Chandigarh. The following sympathetic function tests were performed: 1. Blood pressure response to standing, 2. Cold pressor test, 3. Isometric handgrip test. Results: Our findings on hypertensives showed that there is sympathetic dysfunction and on prehypertensives showed that there is sympathetic overactivity. Conclusion: Autonomic function tests can be used as a routine screening test to predict the future risk of hypertension at an earlier stage and also for a better prognosis during treatment.
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B et al. (2018) studied this question.
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