Why the study?
Does mitral valve repair improve outcomes and reduce complications compared to mitral valve replacement in patients with rheumatic heart disease undergoing aortic valve replacement?
Does mitral valve repair improve outcomes and reduce complications compared to mitral valve replacement in patients with rheumatic heart disease undergoing aortic valve replacement?
In patients with rheumatic heart disease undergoing aortic valve replacement, concomitant mitral valve repair offers comparable survival but significantly less major bleeding than mitral valve replacement.
Answers are grounded in this paper and cite their sources.
May favor mitral repair to reduce bleeding in rheumatic AVR; leaves open need for randomized confirmation of survival equivalence.
From 1992 to 2001, 609 patients with rheumatic heart disease underwent aortic valve replacement with either mitral valve repair (n = 201) or mitral valve replacement (n = 408). Follow-up extended to 10 years. Thirty-day mortality was 1.4% for mitral valve repair and 0.7% for mitral valve replacement (p = 0.4). Survival at 9 years was 96.5 +/- 1.4% after mitral valve repair and 89.7 +/- 7.8% after mitral valve replacement (p = 0.73). Freedom from major bleeding at 9 years was 94.8 +/- 2.4% after mitral valve repair and 81 +/- 7.2% after mitral valve replacement (p = 0.03). Freedom from other valve-related complications and from mitral valve re-operation was similar for the two groups. This study showed that in patients with rheumatic heart disease the results of mitral valve repair with aortic valve replacement were comparable to those of double valve replacement. Major bleeding was less frequent after mitral valve repair with aortic valve replacement. Therefore, whenever feasible, mitral valve repair should be attempted in patients with rheumatic heart disease who need concomitant aortic valve replacement.
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Ho et al. (2004) studied this question.
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