Why the study?
The clinical and biochemical profile of differing LVH phenotypes and their effect on long-term outcomes are ill-defined.
Do concentric and eccentric left ventricular hypertrophy phenotypes increase long-term all-cause mortality in individuals with subclinical cardiovascular disease?
Do concentric and eccentric left ventricular hypertrophy phenotypes increase long-term all-cause mortality in individuals with subclinical cardiovascular disease?
Both concentric and eccentric left ventricular hypertrophy are distinct clinical phenotypes associated with significantly worse long-term all-cause mortality in individuals with subclinical cardiovascular disease.
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LVH phenotypes may aid risk stratification in subclinical CVD; extends observational evidence but leaves open whether modifying hypertrophy improves outcomes.
Ha et al. (2022) studied this question.
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