Why the study?
There is a small number of papers on the effects of hypertension in middle-aged people on the development of cognitive impairment, despite its increasing incidence in young and middle-aged individuals.
Arterial hypertension in middle age is a risk factor for cognitive impairment and dementia, highlighting the importance of blood pressure management to preserve cognitive function.
Impaired cognitive function (CF) is a common manifestation of brain damage as a target organ of arterial hypertension (AH). The presence of hypertension in middle age increases the risk of developing cognitive impairment (CI) and dementia in old age. At the same time, changes in certain indicators characteristic of AH may serve as predictors of CI and dementia in the future. The review presents data on the effects of endothelial dysfunction and increased arterial stiffness on CF. The small number of papers on the effects of hypertension in middle-aged people on the development of CI emphasizes the importance of investigating this topic, as the incidence of CI in young and middle-aged people has increased in recent years.
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Isaykina et al. (2023) studied this question.
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